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News Archive - Scott LaFee

Genetic Changes that Cause Autism Are More Diverse Than Previously Thought

March 24, 2016

The types of gene mutations that contribute to autism are more diverse than previously thought, report researchers at University of California, San Diego School of Medicine in the March 24 online issue of The American Journal of Human Genetics. The findings, they say, represent a significant advance in efforts to unravel the genetic basis of autism spectrum disorder (ASD).

CIRM Grant to Fund Proposed Stem Cell Trials for ALS

March 17, 2016

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine approved yesterday a $6.3 million grant to a research team from the University of California, San Diego School of Medicine and University of California, Davis to pursue a novel human embryonic stem cell-based therapy to rescue and restore neurons devastated by amyotrophic lateral sclerosis or ALS.

Advanced Magnetic Resonance Imaging Technology to Track Cells in the Body

March 14, 2016

The need to non-invasively see and track cells in living persons is indisputable. Emerging treatments using stem cells and immune cells are poised to most benefit from cell tracking, which would visualize their behavior in the body after delivery. Clinicians require such data to speed these cell treatments to patients. Researchers at University of California, San Diego School of Medicine describe a new highly sensitive chemical probe that tags cells for detection by MRI.

Stem Cells Regenerate Human Lens After Cataract Surgery, Restoring Vision

March 9, 2016

Researchers at University of California, San Diego School of Medicine and Shiley Eye Institute, with colleagues in China, have developed a new, regenerative medicine approach to remove congenital cataracts in infants, permitting remaining stem cells to regrow functional lenses.

Moments of Acute Stress Can Cause Molecular Alterations in Immune Response

March 1, 2016

Chronic psychosocial and emotional stress has well-documented negative effects upon the human immune system but less is known about the health effects of acute but transitory episodes of stress. Do panic-inducing moments also raise the risk of stress-related conditions? A team of researchers at University of California, San Diego School of Medicine, Stony Brook University in New York and elsewhere addressed that question by taking blood samples from skydivers to measure key immune response indicators.

Altman Clinical and Translational Research Institute Building Opens March 4

February 29, 2016

Rising above Interstate 5 on the east campus of University of California, San Diego, the Altman Clinical and Translational Research Institute Building (ACTRI), a five-sided polygon of glass, steel and grooved concrete, officially opens its doors March 4 in a ribbon-cutting ceremony.

Predictive Proteins: Elevated Levels Trigger Metastatic Progression of Cancer Cells

February 26, 2016

Researchers at University of California, San Diego School of Medicine and Moores Cancer Center, with colleagues in Spain and Germany, have unraveled how elevated levels of particular proteins in cancer cells trigger hyperactivity in other proteins, fueling the growth and spread of a variety of cancers.

CAR Trials Drive Leukemia and Lymphoma Treatment in New Direction

February 23, 2016

Cancer immunology is based upon boosting the body’s own immune system to vanquish malignancies. It is among the fastest growing areas of oncology research. Researchers at UC San Diego Moores Cancer Center have launched three clinical trials to test the safety and efficacy of a novel cellular-immunotherapy that uses modified T cells – one of the immune system’s primary weapons – to treat three different types of blood cancer that often defy existing therapies.

Longer, Intense Rehabilitation Boosts Recovery after Brain Injury

February 22, 2016

Cognitive and functional recovery after a stroke or traumatic injury requires intense rehabilitative therapy to help the brain repair and restructure itself. New findings by researchers at University of California, San Diego School of Medicine report that not only is rehabilitation vital but that a longer, even more intense period of rehabilitation may produce even greater benefit.

What Makes A Bacterial Species Able to Cause Human Disease?

February 18, 2016

An international team of scientists, led by researchers at University of California, San Diego School of Medicine and the J. Craig Venter Institute (JCVI), have created the first comprehensive, cross-species genomic comparison of all 20 known species of Leptospira, a bacterial genus that can cause disease and death in livestock and other domesticated mammals, wildlife and humans.
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